International  Center  for  Isotope  Effects  Research

Nanjing University

Prof. Hao Xie 

B-211, Modern Engineering Plaza


Research interests

Stable isotope distribution in organic molecules as indicators of metabolisms, climate and basin thermal history; chemical mechanisms in petroleum generation; metabolic paths in higher plants and animals; high resolution mass spectrometry; astrobiology.


2024/02 ­–           Associate Professor, Nanjing University

2021/09 ­– 2024/01.    Postdoctoral Fellow, Pennsylvania State University

2021/07 ­– 2021/09.    Postdoctoral Scholar, California Institute of Technology



2015/09 – 2021/03 Ph.D. in Geochemistry, California Institute of Technology

2011/09 – 2015/06 B.S. University of Science and Technology of China



1.Xie, H., Formolo, M., & Eiler, J. (2022). Predicting isotopologue abundances in the products of organic catagenesis with a kinetic Monte-Carlo model. Geochimica et Cosmochimica Acta, 327, 200-228.

2.Xie, H., Dong, G., Formolo, M., Lawson, M., Liu, J., Cong, F., ... & Eiler, J. (2021). The evolution of intra-and inter-molecular isotope equilibria in natural gases with thermal maturation. Geochimica et Cosmochimica Acta, 307, 22-41.

3.Xie, H., Ponton, C., Formolo, M. J., Lawson, M., Ellis, G. S., Lewan, M. D., ... & Eiler, J. M. (2020). Position-specific distribution of hydrogen isotopes in natural propane: Effects of thermal cracking, equilibration and biodegradation. Geochimica et Cosmochimica Acta, 290, 235-256.

4.Xie, H., Ponton, C., Formolo, M. J., Lawson, M., Peterson, B. K., Lloyd, M. K., ... & Eiler, J. M. (2018). Position-specific hydrogen isotope equilibrium in propane. Geochimica et Cosmochimica Acta, 238, 193-207.

5.Li, X., Xie, H., Birdwell, J. E., McGovern, G. P., & Horita, J. (2023). Intramolecular carbon isotope geochemistry of butane isomers from laboratory maturation and Monte-Carlo simulations of kerogen types I, II, and III. Geochimica et Cosmochimica Acta, 360, 57-67.

6.Mangenot, X., Xie, H., Crémière, A., Giunta, T., Lilley, M., Sissmann, O., ... & Eiler, J. (2023). 2H-2H clumping in molecular hydrogen method and preliminary results. Chemical Geology, 621, 121278.

7.Tyne, R. L., Barry, P. H., Lawson, M., Byrne, D. J., Warr, O., Xie, H., ... & Ballentine, C. J. (2021). Rapid microbial methanogenesis during CO2 storage in hydrocarbon reservoirs. Nature, 600(7890), 670-674.

8.Shuai, Y., Xie, H., Zhang, S., Zhang, Y., & Eiler, J. M. (2021). Recognizing the pathways of microbial methanogenesis through methane isotopologues in the subsurface biosphere. Earth and Planetary Science Letters, 566, 116960.

9.Dong, G., Xie, H., Formolo, M., Lawson, M., Sessions, A., & Eiler, J. (2021). Clumped isotope effects of thermogenic methane formation: insights from pyrolysis of hydrocarbons. Geochimica et Cosmochimica Acta, 303, 159-183.

10.Jautzy, J. J., Douglas, P. M., Xie, H., Eiler, J. M., & Clark, I. D. (2021). CH4 isotopic ordering records ultra-slow hydrocarbon biodegradation in the deep subsurface. Earth and Planetary Science Letters, 562, 116841.

11.Thiagarajan, N., Xie, H., Ponton, C., Kitchen, N., Peterson, B., Lawson, M., ... & Eiler, J. (2020). Isotopic evidence for quasi-equilibrium chemistry in thermally mature natural gases. Proceedings of the National Academy of Sciences, 117(8), 3989-3995.

12.Eiler, J. M., Clog, M., Lawson, M., Lloyd, M., Piasecki, A., Ponton, C., & Xie, H. (2018). The isotopic structures of geological organic compounds. Geological Society, London, Special Publications, 468(1), 53-81.